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Fertility News

Researchers finding few medical differences between 'test-tube' kids and other children



(February 22, 2010) — More than 30 years after the world greeted its first "test-tube" baby with a mixture of awe, elation and concern, researchers say they are finding only a few medical differences between these children and kids conceived in the traditional way.

More than 3 million children have been born worldwide as a result of what is called assisted reproductive technology, and injecting sperm into the egg outside the human body now accounts for about 4 percent of live births, researchers reported Sunday at the annual meeting of the American Association for the Advancement of Science.

The majority of assisted reproduction children are healthy and normal, according to researchers who have studied them. Some of these children do face an increased risk of birth defects, such as neural tube defects, and of low birth weight, which is associated with obesity, hypertension and Type 2 diabetes later in life, the researchers said.

"Overall, these children do well," said Andre Van Steirteghem of the Brussels Free University Center for Reproductive Medicine in Belgium. "It is a reassuring message, but we must continue to follow up."

Carmen Sapienza, a geneticist at Temple University School of Medicine in Philadelphia, noted that few of these test tube children are older than 30, so it's not known if they will be obese or have hypertension or other health problems at age 50 or older.

Sapienza said researchers found differences in 5 percent to 10 percent of chromosome activity levels between assisted reproduction children and other kids.

What's not clear is whether these differences result in some way from assisted reproduction techniques or if they stem from other factors, perhaps ones that caused the couple's in fertility in the first place.  Read more...


Source: Chicago Tribune

 

The Invisible Face of Infertility



By Connie Shapiro, PhD

(Mar 1, 2010)- In thinking about the many faces of in fertility that I mentioned in my last posting, the most prominent one in my mind, ironically, is the invisible face. Adopted by both couples and individuals, this face comes across as having hardly a hint of the developing anguish felt inside. Of course "face" in this context means far more than eyes, nose and mouth. It really captures how you present yourself to the outside world where infertility merits not a word to loved ones, and you resolve to carry on as usual.

If you are in the early months of an infertility workup or the recipient of a recent diagnosis, or if you are someone who guards your privacy, an invisible face may feel like a safe way of figuring out how, whether or when to disclose news of your infertility. "So what's the big deal?" you may ask. Isn't the invisible face a perfectly good option? The answer is both "yes" and "no." I'll start with the reasoning for "yes."

* An infertility diagnosis is an unexpected and an unwelcome piece of news. You need time to digest it, to gather information, to learn from your doctors and to make sense of this with your partner. During that time it can feel best to remain silent on the topic until you believe you have answers for the inevitable questions that others may pose once you become more open about your news.
* You may feel a sense of denial, mixed with hopefulness that this infertility is temporary and will respond to the recommended treatments. In that sense you see no point in getting loved ones all stirred up about something that you hope will be a mere glitch in your plans to build your family.
* Depending on the diagnosis and recommendations for treatment, you may feel in shock as you contemplate medical interventions, lengthy appointments with infertility specialists, and a diminishing bank account. There are no words to capture this jolt in your life, so you initially choose silence.
* You may perceive a diagnosis of infertility as such an assault to your self esteem that you need your invisible face just to be able to hold your head up each day.
* You and your partner may disagree on whether to tell anyone and, if so, how much to reveal. While trying to figure this out, you both adopt the invisible face until you can come up with a plan for disclosing news of your diagnosis and the emotional reactions each of you is having.

All of the "yes" bullets listed above make sense, at least for a time. But after a while, as you and your partner have only one another to turn to for emotional support, you are likely to experience infertility as an increasingly heavy burden. You also may experience it as a source of conflict. Therein lies the foundation for my list of "no's" that target why an invisible face may not be such a good option in the long run...Read more...


Source:
Psychology Today
 

Opsahl, Letterie Among "Best Doctors in America"

The Northwest Center for Reproductive Sciences is proud to announce that Drs. Michael Opsahl and Gerard Letterie have been honored by their election to the 2009-2010 Best Doctors in America for contributions in the field of reproductive medicine. Nomination comes from recommendations of peer physicians and recognizes those who have demonstrated an exceptional commitment to their profession.

Dr. Opsahl is a fellow of the American College of Obstetricians and Gynecologists, a member of the American Society of Reproductive Medicine, the Society for Reproductive Endocrinology and In fertility, and the Society for Assisted Reproductive Technology. His professional interests include male infertility, reproductive aging, oocyte donation, ovarian cryopreservation, statistics and treatment outcome prediction, and reproductive surgery.

Dr. Letterie is a fellow and diplomat in the American College of Obstetricians and Gynecologists  and the American College of Physicians. He is the author of more than 125 scientific articles and has also designed several surgical instruments, including the first catheter for ultrasound guided embryo transfer currently used in several centers world wide. His research interests include fertility preservation in cancer patients through hormonal protection and oocyte freezing and as an elective option in patients who want to preserve fertility.
 

AP: Genetic disease testing leads some adults not to have kids


Some of mankind's most devastating inherited diseases appear to be declining, and a few have nearly disappeared, because more people are using genetic testing to decide whether to have children. Births of babies with cystic fibrosis, Tay-Sachs and other less familiar disorders seem to have dropped since testing came into wider use, The Associated Press found from interviews with numerous geneticists and other experts and a review of the limited research available.

Many of these diseases are little known and few statistics are kept. But their effects — ranging from blood disorders to muscle decline — can be disabling and often fatal during childhood.

Now, more women are being tested as part of routine prenatal care, and many end pregnancies when diseases are found. One study inCalifornia found that prenatal screening reduced by half the number of babies born with the severest form of cystic fibrosis because many parents chose abortion.

More couples with no family history of inherited diseases are getting tested before starting families to see if they carry mutations that put a baby at risk. And a growing number are screening embryos and using only those without problem genes.

The cost of testing is falling, and the number of companies offering it is rising. A 2008 federal law banning gene-based discrimination by insurers and employers has eased fears. Read more...

Source: USA TODAY
 

Researchers: Most 'Test Tube' Kids Are Healthy


(February 21, 2010)--More than 30 years after the world greeted its first "test-tube" baby with a mixture of awe, elation and concern, researchers say they are finding only a few medical differences between these children and kids conceived in the traditional way.

More than 3 million children have been born worldwide as a result of what is called assisted reproductive technology, and injecting sperm into the egg outside the human body now accounts for about 4 percent of live births, researchers reported Sunday at the annual meeting of the American Association for the Advancement of Science.

The majority of assisted reproduction children are healthy and normal, according to researchers who have studied them. Some of these children do face an increased risk of birth defects, such as neural tube defects, and of low birth weight, which is associated with obesity, hypertension and Type 2 diabetes later in life, the researchers said....Read more...

Source: NPR

 
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